Ketamine Emre Yılmazoğlu

Ketamine Has Been Used As An Anesthetic For Many Years. After The 1950S, İt Was Found To Have An Antidepressant-Like Effect When Used İn Low Doses. Although İt İs Not Widely Prescribed Due To İts Potential For Abuse, Studies To Unravel İts Mechanisms Of Action Are Quite Abundant. In Addition To Being An Antagonist Of Nmda And Ampa Receptors, İt İs Also Effective On Monoaminergic And Opioid Systems. The Prominent Features Of Ketamine Are That İt Acts On Metabolism İn Different Ways, Has A Much Faster And Longer-Lasting Effect Than Traditional Antidepressants, And Especially İts Performance İn Patients Who Are Resistant To Treatment. R- Or S-Ketamine Enantiomers, Or Their Racemic Mixture, Have Been Studied İn Both Preclinical And Clinical Studies. The Conclusion Drawn From These Studies İs That All The Properties Of Ketamine Will Be Elucidated İn The Coming Years And That İt Will Be Used As A Safe Antidepressant For Patients Suffering From Depression.